LINC01133 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells by upregulating CTNNB1 by acting as a sponge for miR-214-3p
Source: Journal of Orthopaedic Surgery and Research
Marrow mesenchymal stem cell (MSC) dysfunction is associated with the pathogenesis of OP. MSCs are widely distributed in various organs and tissues and are the preferred cell type for bone regeneration. Among adult stem cells, bone marrow mesenchymal stem cells (BMSCs) are considered the most suitable option for bone tissue engineering due to their ability to self-renew, high differentiation potential, and low immunogenicity.
