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Adipose-derived mesenchymal stem cells combined with platelet-rich plasma are superior options for the treatment of osteoarthritis

Source: Journal of Orthopaedic Surgery and Research

There is currently no definitive treatment for osteoarthritis. We examined the therapeutic effects and underlying mechanisms of platelet-rich plasma (PRP) and adipose-derived mesenchymal stem cells (ADSCs), individually or in combination, in a rat model of anterior cruciate ligament-induced degenerative osteoarthritis (OA) of the knee. This study seeks to advance clinical approaches to OA treatment.

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  • American Orthopaedic Society for Sports Medicine
  • American Association of Nurse Anesthesiology
  • RYC Orthopedics
  • American Academy of Orthopaedic Surgeons
  • International Society for Hip Arthroscopy
  • Kerlan Jobe Orthopaedic Clinic
  • NYU Langone Medical Center
  • American Board of Orthopaedic Surgery
  • Yale University
  • OrthoEnglewood