News Updates
PRP, stem cells may provide a positive impact for knee OA
Source: Healio
Leukocyte-poor platelet-rich plasma, adipose derived stem cells and bone marrow aspirate concentrate may have a positive impact on knee osteoarthritis, according to a presenter at the Current Concepts of Joint Replacement Winter Meeting.
Stem cell therapy reduces need for nearly 10% of hip replacements
Source: Medical Xpress
Daniel Wiznia, MD, an orthopedic surgeon with Yale School of Medicine, is practicing a surgical technique designed to render 10% of hip replacements unnecessary.
Stem cell–based bio-implant to repair cartilage and delay joint degeneration
Source: Medical Xpress
A novel off-the-shelf bio-implant containing embryonic stem cells has the potential to revolutionize the treatment of cartilage injuries
Sanford opens groundbreaking stem cell trial for osteoarthritis
Source: SiouxFalls.Business
The ENDURE trial is a first-of-its-kind study, Sanford said. Adults with a diagnosis of osteoarthritis in the wrist, knee, ankle, shoulder or hip are eligible to participate in the clinical trial. The study is regulated through the Food and Drug Administration, and the cells are tested for quality and safety before injection, Sanford said.
Power of stem cells harnessed to create cartilage tissue
Source: Medical Xpress
Researchers at the University of Southampton have invented a new way to generate human cartilage tissue from stem cells. The technique could pave the way for the development of a much-needed new treatment for people with cartilage damage.
Hope For Those Aching Joints
Source: Forbes
At long last, there seems to be real hope in rebuilding damaged articular cartilage. Researchers from the University of Southampton recently discovered a new method to generate cartilage tissue from stem cells. Articular cartilage covers the ends of bones and acts as a shock absorber in the joints.
Researchers identify core genetic networks driving human embryonic stem cell behavior
Source: Science Daily
At the earliest stages of human embryonic development, a small collection of cells known as human embryonic stem cells (hESCs) orchestrates growth and differentiation, eventually giving rise to highly specialized human tissues. As pluripotent cells -- progenitors of every type of cell type in the body -- hESCs are of central interest to developmental and regenerative biologists. Many genes driving hESC functioning have previously been identified, but powerful tools that shed light on the interrelated activities of these genes have only emerged more recently. Researchers from Brigham and Women's Hospital and Harvard Medical School used genome-wide genetic screening to both over-express and inactivate ("knock out") tens of thousands of genes in hESCs. They uncovered key networks that simultaneously control pluripotency and readiness for cell death (apoptosis), helping to ensure optimal conditions for embryonic development. The study's findings, published in Genes and Development, offer new insights into cancer genetics and a novel approach for regenerative medicine research.
